R. Gaspari repliedb. Pilocarpine antagonizes peripherally, but it won't cross the blood brain barrier, so that's why I'd select Physostigmine by slow IV injection.

gangadharan_nair repliedThe antidote to atropine is physostigmine or pilocarpine.
Antidote: To reverse life-threatening central and peripheral effects of atropine and substitutes, give physostigmine salicylate, 1-5 ml IV of dilution containing 1 mg in 5 ml of saline. The smaller dose is for children, and injection should take not less than 2 minutes.ECG control is advisable. Dosage can be repeated every 5 minutes up to a total dose of 2 mg in children and 6 mg in adults every 30 minutes. Physostigmine is contraindicated in hypotensive reactions. Atropine (1 mg) should be available for immediate injection if physostigmine causes bradicardia, convulsions, or severe broncho-constriction.

John de Witt repliedFor those who haven't used it, physostigmine is the answer. Nasty! None of the drugs you list are exactly useful in the general treatment of the anticholinergic toxidrome.

MTD repliedThere are much better drugs than the ones you listed for atropine intox. But in your question B: pilocarpine is the best choice b/c its a Ach Agonist.